While various treatment options are available, oral medications and injection therapy are two of the most widely used approaches. This article compares these two treatment methods, exploring their efficacy, advantages, and suitability for different patients.
1. Oral medications for ED treatment
Oral medications, precisely phosphodiesterase type 5 (PDE5) inhibitors, are often used to treat ED. PDE5 inhibitors increase nitric oxide, which relaxes muscles in the penis. This increased relaxation improves blood flow, facilitating and maintaining an erection when sexual stimulation occurs.
Advantages of Oral medications
- Convenience – Easy to take and non-invasive
- Efficacy – Effective for a large percentage of men with ED
- Onset of action – Some work within 15-30 minutes
- Duration – Effects last from a few hours to up to 36 hours, depending on the medication
- Alprostadil
- Phentolamine
- Papaverine
- Combinations of the above (e.g., Trimix, Bimix)
- High efficacy – Be effective for up to 90% of men with ED
- Rapid onset – Usually works within 5-15 minutes
- Not affected by food or alcohol consumption
- Be effective for various causes of ED, including severe cases
- Potentially longer-lasting erections compared to oral medications
- Efficacy rate – Approximately 70-80% overall
- Patient satisfaction – Generally high due to ease of use and non-invasive nature
- Best suited for – Mild to moderate ED, mainly when caused by psychological factors or mild vascular issues
- Efficacy rate – Up to 90%, even in cases where oral medications have failed
- Patient satisfaction – High among those who overcome initial hesitation about injections
- Best suited for – Moderate to severe ED, including cases with neurological or severe vascular causes
- Often covered by insurance plans
- Generic versions available for some medications, reducing costs
- Long-term use is expensive if insurance coverage is limited
- Initial costs may be higher due to the need for supplies and training
- Per-use cost is lower than some oral medications
- May not be covered by all insurance plans